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KMID : 0191120140290040599
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Journal of Korean Medical Science
2014 Volume.29 No. 4 p.599 ~ p.603
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A Case of IgG4-Related Disease with Bronchial Asthma and Chronic Rhinosinusitis in Korea
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Lee Young-Soo
Cho Hyo-Jeong
Yoo Hye-Soo
Shin Yoo-Sub
Park Hae-Sim
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Abstract
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IgG4-related disease (IgG4-RD) is characterized by a systemic involvement of tumor-like lesions with IgG4-positive plasmacytes. We experienced a case of IgG4-RD developed in a patient with bronchial asthma (BA) and chronic rhinosinusitis (CRS). A 55-yr-old female patient with BA and CRS complained of both eyes and neck swelling as well as a recurrent upper respiratory infection in recent 1 yr. The serum levels of IgG4, creatinine, and pancreatic enzymes were elevated. A biopsy of the submandibular gland showed an abundant infiltration of IgG4-positive plasmacytes. Her symptoms remarkably improved after the treatment of a systemic steroid that has been maintained without recurrence. We report a rare case of IgG4-RD developed in a patient with BA and CRS.
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KEYWORD
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IgG4-Related Disease, Asthma, Bronchitis, Chronic
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